Now that I can actually read some things in the game without getting a headache (thanks to some great efforts from the community), some other reactions:
UI layout is still terrible even with color changes. The use of space is very inefficient. Font sizes are way too small. The change in colors, as others have mentioned, makes no sense, and feels very much as change for the sake of change and not change to make the game better.
There are too many hidden menus and hidden clickable things. It's frustrating. I'm clicking all over the screen trying to find something that might be hidden. I can't change a worker's role without clicking on one of their existing roles on their roster profile, and if they have no roles I have to click where it says how the fans perceive them to get to roles. This makes zero sense.
Not being able to scroll with a mouse wheel is utterly inexcusable.
Forcing players to grow their companies in a certain way by making the size requirements so specific takes some of the fun and creativity out of the game. Maybe I don't want to expand my company the way I'm forced to in order to achieve the next size level.
I can't find where to assign a manager to a worker, or to see who a manager's clients are.
When I look at the Creative screen and click on a worker in one of the lists, it shows me their profile as if they don't work for me even if they do. So I can't see, for example, their contract information, without backing out, going to the roster, and opening their profile again.
Forcing players to use predefined products that can't be customized or tweaked also seems unnecessary.
Minimum number of storylines seems a bit too high for some products.
The handbook is barely useful. Clicking a question mark on a screen only sometimes takes me to the relevant part of the handbook. It should be a PDF or a Word document that we can search through.
This is just what I've come across in the last half hour or so of poking around. The whole experience of this game is one of frustration and disappointment. It feels like a massive step back from 2016, filled with lots of changes that were only made for the sake of changing things and not to make a better game. And I've been playing since EWR, so I can't imagine how much of a turn-off this game would be for someone trying out the series for the first time. Without some serious fixing I won't be buying, and it makes me really sad to say that, because I was really looking forward to this game.